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Other Infections

Naloxone Is Cost-effective Way to Prevent Heroin Overdose Deaths

Distributing naloxone more widely to heroin users would reduce the number of deaths due to overdose and would be a cost-effective intervention, according to a mathematical model described in the January 1, 2013,Annals of Internal Medicine. Providing naloxone to prescription opiate users would prevent even more deaths.

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Bedaquiline Approved for Multidrug-resistant Tuberculosis after Long Wait

The U.S. Food and Drug Administration last week approved bedaquiline (brand name Sirturo, formerly TMC207) as part of a combination regimen for adults with multidrug-resistant pulmonary tuberculosis (TB) -- the first approval of a new TB drug in more than 40 years.

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Human Papillomavirus Vaccination Can Protect Many Women with HIV

HIV positive women may benefit from immunization against cancer-causing human papillomavirus (HPV) types, even though they are likely to have been exposed to some types of the virus previously, according to a study in the November 1, 2012, Journal of Acquired Immune Deficiency Syndromes. A majority of study participants remained susceptible to the most common high-risk types, HPV-16 and HPV-18.alt

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2012-2013 Could Be Bad Flu Season, Not Too Late to Get Vaccine, CDC Advises

Significant increases in influenza activity in the U.S. during the past 2 weeks indicate that this year's flu season has come early, and it could be a bad one, according to the Centers for Disease Control and Prevention (CDC). December 2-8 is National Influenza Vaccination Week, and it's not too late to get yours.alt

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Topical Cidofovir Effective and Well-tolerated for Anal and Vulva Neoplasia

A topical formulation of the antiviral drug cidofovir (Vistide), best known as a treatment for cytomegalovirus (CMV), also appears effective for short-term treatment of high-grade anal and vulva cancer caused by human papillomavirus (HPV) in people with HIV, according to a report in the October 1, 2012, advance online edition of AIDS. alt

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FDA Committee Supports Accelerated Approval of TB Drug Bedaquiline

The U.S. Food and Drug Administration (FDA) Anti-Infective Drugs Advisory Committee this week gave a favorable opinion on Janssen's request for accelerated approval of its investigational tuberculosis drug bedaquiline (also known as Sirturo, formerly TMC207) for treatment of multidrug-resistance TB (MDR-TB).

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WHO: TB Rates Fall, but Drug Resistance Still a Concern

Rates of new tuberculosis (TB) cases and deaths have declined and approximately 20 million people worldwide are alive due to TB care and control efforts, but too little is being done to address multidrug-resistant TB, according to the World Health Organization's Global Tuberculosis Report 2012.alt

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ICAAC 2012: Cobicistat-boosted Elvitegravir Does Not Interact with Methadone

The new HIV integrase inhibitor elvitegravir, boosted with cobicistat, does not cause clinically important changes in levels of methadone or buprenorphine used to manage opiate addiction, researchers reported at the recent 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) in San Francisco.alt

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CDC Recommends Pneumococcal Vaccine Combo for Immune Compromised People

Immunocompromised individuals, including people with HIV, should receive both the 13-valent pneumococcal conjugate vaccine Prevnar 13 and the 23-valent pneumococcal polysaccharide vaccine Pneumovax 23 to prevent pneumococcal pneumonia and invasive disease, according to the latest recommendations from the Centers for Disease Control and Prevention (CDC). alt

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