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Other Infections

Coffee Consumption Linked to Lower Risk of Death in Large Study

Drinking up to 6 cups of coffee per day was associated with significantly reduced risk of death over 13 years, according to a large prospective analysis of people in the 50-70 year age range, published in the May 17, 2012, New England Journal of Medicine.alt

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Researchers Identify Compounds that May Block HPV's Ability to Cause Cancer

Researchers have identified a set of compounds known as thiadiazolidinediones that interfere with the ability of human papillomavirus (HPV) to disable a key tumor suppressor protein, offering a potential new approach to treatment, according to a report in the April 20, 2012, issue of Chemistry & Biology. alt

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Hepatitis E Uncommon among HIV+ People, but May Cause Unexplained Liver Enzyme Elevations

Coinfection with hepatitis E virus (HEV) is not commonly seen in people with HIV, according to 2 recent reports, but it is a possibility to consider if a person has elevated liver enzymes not attributable to another apparent cause.

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March 24 is World TB Day

Tuberculosis (TB) is the leading cause of death for people with HIV worldwide -- killing approximately 350,000 people in 2010 -- and the second leading cause for the population as a whole. Globally, an estimated 12 million people are living with latent TB. In the U.S., more than 10,500 new TB cases were reported in 2011, mostly in HIV negative people. Multidrug-resistant (MDR), extensively drug-resistant (XDR), and totally drug-resistant (TDR) TB are a growing concern.

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Researchers Report Setbacks on Herpes Simplex Vaccine and Treatment

An experimental herpes simplex virus (HSV) vaccine partially protected women against infection with HSV type 1 but not type 2, according to a recent report in the New England Journal of Medicine. Another recent study found that antiviral treatment with acyclovir (Zovirax) or valacyclovir (Valtrex) did not prevent periodic HSV-2 reactivation and viral shedding.alt

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WHO Releases Updated TB/HIV Guidance, Claims Nearly 1 Million Lives Saved

The World Health Organization (WHO) reported that more than 900,000 lives were saved over the past 6 years by increased screening and treatment of both HIV and tuberculosis (TB) around the world. Globally, TB is the leading cause of death for people with HIV. This month WHO released updated TB/HIV guidelines for national programs and stakeholders.alt

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Gonorrhea May Become Untreatable Due to Resistance, Experts Warn

Neisseria gonorrhoeae,the bacteria that cause gonorrhea, are becoming increasingly resistant to existing drugs and more difficult to treat in the U.S., public health experts warn in the February 9, 2012, New England Journal of Medicine.

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CROI 2012: Community-wide Isoniazid Prevention Did Not Improve TB Control in South African Mines

Giving a 6- to 9-month course of isoniazid preventive therapy (IPT) at a "community-wide level" -- to everyone working at randomly selected South African gold mines -- had no effect on tuberculosis (TB) incidence, TB prevalence, or all-cause mortality in the population, when compared to a cluster of gold mines randomized to standard TB program management, according to the Thibela TB study, the largest IPT intervention study ever to be conducted.alt

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New Shorter Treatment for Latent TB Not Recommended for HIV+ People on ART

Expert panels that put together the Department of Health and Human Services antiretroviral therapy (ART) guidelines have advised that the shorter and simpler combination regimen for latent tuberculosis (TB) recently recommended by the Centers for Disease Control and Prevention (CDC) is not suitable for people being treated for HIV.

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