HIV/AIDS Topics EACS 2011: Neurocognitive Impairment in People with HIV
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- Category: Neurocognitive Problems
- Published on Thursday, 13 October 2011 00:00
- Written by Gus Cairns
How much more common is brain impairment and dementia in people with HIV than in the general population? A study presented at the 13th European AIDS Conference (EACS 2011) this week in Belgrade showed that the answer could vary from "no more common" to "4 times as common," according to which group you studied, which sample of the HIV negative population you compared them with, and whether you averaged their neurocognitive (NC) performance over all domains or picked out specific areas of impairment.
Elevated Triglycerides and Waist Circumference Predict Cardiovascular Risk for People with HIV
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- Category: Cardiovascular Disease
- Published on Tuesday, 11 October 2011 00:00
- Written by Liz Highleyman
HIV positive people with high triglyceride levels and large girth were more likely to have other risk factors associated with cardiovascular disease and events such heart attacks, suggesting that these 2 simple measures may be used to distinguish high-risk versus low-risk individuals, according to a study in the September 22, 2011, edition of the open access journal PLoS ONE.
Cryptococcus May Be Misdiagnosed in People with AIDS
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- Category: Opportunistic Illness (OIs)
- Published on Tuesday, 06 September 2011 00:00
- Written by Duke University
People with AIDS who contract cryptococcal infection may have a different organism than usually suspected, Cryptococcus gattii rather than Cryptococcus neoformans, according to a study in the September 1, 2011, online edition of PLoS Pathogens. Prevalence of C. gattii varies by region, and correct identification can help select the most effective treatment.
Function Imaging Changes May Reflect Brain Impairment during Early HIV Infection
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- Category: Neurocognitive Problems
- Published on Friday, 07 October 2011 00:00
- Written by Mary Ann Leibert
Functional magnetic resonance imaging during the early stages of HIV disease reveals changes in connectivity in the brain that may be due to high-level viral replication soon after infection, according to a study in the September 20, 2011, issue of Brain Connectivity. Researchers suggested this method may be useful as a non-invasive marker for future neurocognitive impairment.
Age-Related Fractures Due to Reduced Bone Quality as well as Quantity
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- Category: Bone Loss
- Published on Tuesday, 30 August 2011 00:00
- Written by Lawrence Berkeley National Laboratory
Bone loss is a growing concern as the HIV positive population ages. Age-associated bone problems including fractures have largely been attributed to loss of bone mineral density (osteopenia and osteoporosis), but changes in the quality of bone structure play a role as well, according to recent research described in the August 22, 2011, advance edition of Proceedings of the National Academy of Sciences. 
HIV+ People on ART Have Stable Bone Density after Short-term Loss
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- Category: Bone Loss
- Published on Tuesday, 13 September 2011 00:00
- Written by Liz Highleyman
People with HIV tend to experience a loss of bone mineral density soon after starting antiretroviral therapy (ART), but the decline reaches a plateau after about 1 year and remains quite stable thereafter, according to a meta-analysis of nearly 40 studies described in the September 2011 Journal of Clinical Endocrinology and Metabolism.
Diet, Exercise, and Niacin/Fenofibrate Improves Blood Lipids in People with HIV
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- Category: Cardiovascular Disease
- Published on Tuesday, 30 August 2011 00:00
- Written by Liz Highleyman
A combination approach including low-fat diet, exercise, and niacin plus fenofibrate increased HDL good cholesterol and reduced bad cholesterol and triglycerides in HIV positive people on antiretroviral therapy (ART) with abnormal blood lipid levels, researchers reported in the July 2011 Journal of Clinical Endocrinology and Metabolism.
FDA Considers Limits on Osteoporosis Drugs Due to Fracture Risk
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- Category: Bone Loss
- Published on Monday, 12 September 2011 00:00
- Written by Liz Highleyman
An advisory committee of the U.S. Food and Drug Administration (FDA) last week weighed the risks and benefits of bisphosphonate drugs such as alendronate (Fosamax) for managing osteoporosis. The committee recommended limiting the duration of bisphosphonate use, but did not agree on a time frame.
Non-AIDS Cancers Linked to Lower CD4 Count in People with HIV
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- Category: Cancer/Malignancies
- Published on Tuesday, 02 August 2011 00:00
- Written by Matt Sharp
HIV positive people who spent more time with a CD4 cell count < 200 cells/mm3 had a higher risk of developing non-AIDS cancers, in particular those related to infectious causes, according to findings from the Dutch ATHENA cohort published in the June 15, 2011, issue of Clinical Infectious Diseases.
More Articles...
- IAS 2011: People with HIV Have Double Risk for Non-Melanoma Skin Cancers
- IAS 2011: Doubt Remains if HIV Therapy Increases the Risk of Fragility Fractures
- IAS 2011: Cognitive Impairment is Common, but ART Reduces Risk
- IAS 2011: Coronary Artery Calcification Linked to Bone Loss
- IAS 2011: Transplants Safe for HIV+ People but HCV Adds Risk
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