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Hepatitis B

Prolonged Entecavir for Slow Responders

Treatment-naive hepatitis B patients who stay on entecavir (Baraclude) monotherapy despite suboptimal response at 48 weeks are likely to go on to achieve undetectable viral load. alt

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Mothers with Hepatitis B Can Safely Breastfeed

Women with chronic HBV infection can breastfeed with minimal risk of transmitting the virus to their babies if they use standard prophylactic therapy, according to a recent review.

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Switch to Lamivudine Not as Effective as Staying on Entecavir

Hepatitis B patients who switch to cheaper lamivudine (Epivir-HBV) after achieving undetectable HBV viral load and normal ALT on entecavir (Baraclude) are more likely to experience viral rebound. alt

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Is Hepatitis B Under-treated in U.S.?

As few as 5% of the approximately 1.4 to 2.0 million people with chronic hepatitis B in the U.S. are tested, enter care, and are successfully treated, according to a recent review. alt

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HBV Rebound Common in Patients Taking Oral Meds

Nearly half of patients taking nucleoside/nucleotide analogs to treat hepatitis B experienced viral breakthrough over 5 years, and about 40% of these were not attributable to drug resistance mutations. alt

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DHHS Releases Viral Hepatitis Action Plan

New DHHS report details plan for prevention, care, and treatment of hepatitis B and C. alt

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Additional HBV Vaccine Dose Offers More Protection for People with HIV

Two alternative dosing schedules of hepatitis B virus (HBV) vaccination led to higher levels of protection than the standard 3-dose schedule. alt

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Tenofovir Improves Outcomes of HBV Acute-on-Chronic Liver Failure

Treatment with tenofovir (Viread) lowers HBV viral load, reduces liver injury, and decreases the risk of death in patients with acute-on-chronic liver failure due to hepatitis B reactivation.

 

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Immune-Based Therapy GS-9620 Shows Promise for Hepatitis B

Gilead's GS-9620, an experimental TLR7 agonist, stimulated interferon production and activated B-cells and T-cells in laboratory and human studies, and was active against hepatitis B and a related virus in monkeys and woodchucks, researchers reported at EASL 2011.

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